The Buddha’s sacred last words:
vayadhammā saṅkhārā appamādena sampādetha
All compounded things, all experiences (mental and physical), all phenomena by their very nature decay and die, and are disappointing: it is through being not-blind-drunk on, obsessed by, or infatuated with, the objects of the senses that you succeed in awakening, or obtain liberation.
Or more succinctly:
All things are disappointing, [it is] through vigilance [that] you succeed.